Hamblin On CLL

Updated 26/1/08

If you have CLL and you are reading this, you have heard of Terry Hamblin. He is one of the world’s experts on the subject of Chronic Lymphocytic Leukaemia. Now retired, he doesn’t seem to have stopped working. On his blog, Mutations Of Mortality he states the following – “Professor of Immunohaematology Southampton 1986 to present. I now work part time researching, writing, reviewing, editing, speaking, sitting on committees, advising, answering questions and thinking.” His blog must take up some considerable time as well. There are ninety eight posts on the subject of CLL, and if you want to read them, you have to read the whole blog, as there is no index at present. Until now. The rest of this post links to all the CLL related posts on Mutations of Mortality.

If you are new to CLL, then read the following three posts, “What is the aim of treatment” Part 1Part 2Part 3. At the same time read “Who Needs Treatment?” – this will give you a balanced start in the process of learning about CLL. I think you should also read “Alternative Medicine” too, also as part of a sensible introduction to the illness.

What follows is a reverse chronological order list of all ninety eight posts, by title. That means that the most recent is first, and the oldest is last, like in all good blogs.

History Of CLL (Part 5) To The End Of The Millenium 16th Feb 2008

History Of CLL (Part 4) Complications 16th Feb 2008

History Of CLL (Part 3) Clinical Staging 16th Feb 2008

History Of CLL (Part 2) The Twentieth Century 16th Feb 2008

History Of CLL (Part 1) Historical Aspects Of CLL 15th Feb 2008

MCV (Mean Corpuscular Volume) 25th Jan 2008

Transplants in CLL 13th Jan 2008

Secondary Malignancies 6th Jan 2008

Secondary MDS And Acute Leukaemia 3rd Jan 2008

Anti Oxidants 7th Dec 2007

Quality of life 6th Dec 2007

Escalating Cost Of Cancer Drugs 4th Dec 2007

Vaccination Against Pneumonia 19th Nov 2007

Stem Cell Transplant, A Lifelong Commitment

Hope For P53 Mutants

Up To Date On CD38

Late Treatment In CLL

Early Stage Treatment

Leukaemic Stem Cells

Guidelines For Clinical Trials

Jab And Dab

Del 11q23 (a clarification for CLLers with deleted 11q23)

CLL Guidelines

Chromosomes At IWCLL

IWCLL 2007

Discoverer Of Leukaemia

How Many Mutations Are You Allowed?

Radiation And CLL

Alternative Medicine

Secondary Leukaemia

97, 98, 99, 100

beta 2 microglobulin

Prognostic Markers In Bournmouth

Borderline Mutated

To Treat Or Not To Treat (this post was written after the untimely death of Kurt Grayson)

Watching And Waiting Too Long (this one too)

Why Should I Get My Prognostic Markers Done?

Zap-70 Again

CT Scans

Bringing New Drugs To Trial

Consolidation Therapy With Alemtuzumab

Minimum Residual Disease

Bone Marrow Transplantation For CLL

The Label Came Off (About NICE, the FDA and Big Pharma)

Treatment Of CLL (First draft of an article for The Lancet)



CLL Mistakes (Mistakes non specialists might make)

Chemotherapy Combinations

Surrogate Markers

More On Chlorambucil

NICE Work (xx)


What Questions Should I Ask The Doctor?

What Is The Aim Of Treatment Part 1Part 2Part 3


Imiquimod Trial 3

Imiquimod Trial Part 2

Imiquimod Trial Part 1

Splenic Marginal Zone Lymphona (SMZL)

Weight Loss In CLL

Chlorambucil Plus Rituximab

Fatigue In CLL

Monoclonal Antibodies 4

Monoclonal Antibodies 3: mainly About Campath

Monoclonal Antibodies Part 2: Rogers Brambell

Nutlins (Good with purine analogues)

Fludarabine And Prednisolone

Steroids 3

Monoclonal Antibodies In CLL

Diagnosing ITP

Consultation Document 2

Consultation Document

PARP Inhibitors

Micro RNAS

Outcomes In Clinical Trials

Steroids 2


Steroids 1

Spleen 3

Spleen 2

Spleens 1

Fludarabine Combinations

Blood Transfusion

Who Needs Treatment

Beta Glucan To Enhance Rituximab

CAT Scans

Bone Marrow Aspirates And Trephine Biopsies

Soluble cd-23


Beta 2 Microglobulin

Other Prognostic Factors – Doubling Time

Publication Ehics

CLLs and VH Mutation Graph (My Own Title)

Lack Of Correlation Graph (My own title)

Graph From Chiorazzi (Illustrating cd38 as a prognostic marker)

CD 38

One Picture Is Worth A Thousand Words (Survival curve)

VH Mutations

Frozen In Time

A Diagram Of The Heavy Chain Immunoglobulin Genes

B Cell Receptor

Natural History Of CLL



How Do You Know If You Have CLL

What Is Chronic Lymphocytic Leukaemia?

What Is It Here For?

That is a lot of information, ranging from the basic introductory stuff for the newly diagnosed, to teh most cutting edge research of teh illness.

Endearingly, teh Professor’s cavalier attitude to teh word teh, shines through his blog. I hope this little index will be useful to those of us seeking to learn. I shall try to keep it up to date.

  1. Wayne Wells
    January 21, 2008 at 3:13 am

    Thanks Andy,
    A great service to consolidate what most of us are after.

  2. Jan Buskell
    November 29, 2008 at 11:41 am

    Oh boy, am I ever glad to see this list, Andy! Thanks so very much for putting it together. In just a moment, I’ll have it bookmarked.

    Jan *teh* wife of Kelly – about to take his last 4-day round of FCR

  3. March 6, 2009 at 9:24 am

    Wow.What a great site this is ! :-). Thought I would just “drop by” after reading your response to my post on my Scirocco2morocco blog page.
    Keep up the good work :-).Andy

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